As is usual with mysterious "permission denied" errors, SELinux was the underlying cause. ...
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ID Status Resolution Sev Product Comp Assignee Reporter Summary
9132 CLOS FIXE maj Sisyphus emacs22- eugvv mhz Segmentation fault when closing frame (C-x 5 0)

File a new bug in the "emacs22-X11-gtk" component of the "Sisyphus" product